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Bryostatin 2

SIGMA/SML1266 - ≥95% (HPLC)

Synonym: (+)-Bryostatin 2; (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-Tetrahydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-

CAS Number: 87745-28-6
Empirical Formula (Hill Notation): C45H66O16
Molecular Weight: 863.00
Linear Formula: C45H66O16
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1266-10UG 10 µg
 $291.00
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥95% (HPLC)
biological source Bugula neritina (sponge)
color colorless to light yellow
form film
InChI 1S/C45H66O16/c1-9-10-11-12-13-14-37(49)59-41-29(21-39(51)56-8)20-32-24-35(27(2)46)58-40(52)23-30(47)22-33-25-36(48)43(5,6)44(53,60-33)26-34-18-28(19-38(50)55-7)17-31(57-34)15-16-42(3,4)45(41,54)61-32/h11-16,19,21,27,30-36,41,46-48,53-54H,9-10,17-18,20,22-26H2,1-8H3/b12-11+,14-13+,16-15+,28-19-,29-21+/t27-,30-,31?,32?,33-,34+,35-,36+,41+,44+,45-/m1/s1
InChI key LIPGUSBNMQRYNL-WZYRAJGLSA-N
Quality Level 100 
shipped in wet ice
SMILES string O1[C@]2(C[C@H]3OC(CC(=CC(=O)OC)C3)C=CC([C@@]4(OC(C[C@@H](OC(=O)C[C@@H](C[C@@H]1C[C@@H](C2(C)C)O)O)[C@H](O)C)CC(=C/C(=O)OC)[C@@H]4OC(=O)C=CC=CCCC)O)(C)C)O
storage temp. −20°C
Biochem/physiol Actions: Bryostatin 2 is potent protein kinase C activator (Ki = 5.9 nM) and an antagonist to phorbol ester tumor promoter 12-0-tetradecanoylphorbol-13-acetate (TPA). Bryostatin 2 exhibits antineoplastic activity against the murine P388 lymphocytic leukemia and human U937 cells.
Biochem/physiol Actions: Bryostatin 2 is potent protein kinase C activator and an antagonist to phorbol ester tumor promoter TPA.
Packaging: 10 μg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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