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Bryostatin 3

SIGMA/SML1267 - ≥95% (HPLC)

Synonym: [4S-[4R*(2E,4E),5R*,7E,9S*,11Z,13R*,15R*,17R*,19S*,21S*,25S*(S*),27S*,27aR*]]-2,4-Octadienoic acid,17-(acetyloxy)-4,5,6,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,25,26,27,27a-docosahydro-5,15,21-trihydroxy-25-(1-hydroxyethyl)-11-(2-methoxy-2-oxoethylidene)-6,6,16,16-tetramethyl-2,23-dioxo-5,27:9,13:15,19-triepoxy-2H-furo[2,3-e]oxacyclohexacosin-4-yl ester

CAS Number: 143370-84-7
Empirical Formula (Hill Notation): C46H64O17
Molecular Weight: 888.99
Linear Formula: C46H64O17
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1267-10UG 10 µg
 $234.00
1/EA		 Add To Favorites
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assay ≥95% (HPLC)
biological source Bugula neritina (sponge)
color colorless to light yellow
form film
InChI 1S/C46H64O17/c1-9-10-11-12-13-14-37(50)61-42-33-23-40(53)60-41(33)35-24-34(26(2)47)59-39(52)21-29(49)20-31-22-36(57-27(3)48)44(6,7)45(54,62-31)25-32-18-28(19-38(51)56-8)17-30(58-32)15-16-43(4,5)46(42,55)63-35/h11-16,19,23,26,29-32,34-36,41-42,47,49,54-55H,9-10,17-18,20-22,24-25H2,1-8H3/b12-11+,14-13+,16-15-,28-19+/t26-,29-,30+,31-,32+,34-,35-,36+,41+,42+,45+,46-/m1/s1
InChI key BSNHYLUEHJOXFN-UUIHWDITSA-N
Quality Level 100 
shipped in wet ice
SMILES string O1[C@H]2[C@H]3OC(=O)C=C3[C@@H]([C@@]1(C(C=C/[C@@H]4O[C@H](C[C@@]5(O[C@@H](C[C@@H](C5(C)C)OC(=O)C)C[C@H](CC(=O)O[C@H](C2)[C@H](O)C)O)O)CC(=CC(=O)OC)C4)(C)C)O)OC(=O)C=CC=CCCC
storage temp. −20°C
Biochem/physiol Actions: Bryostatin 3 is a potent protein kinase C activator with a Ki of 2.75 nM, and an antagonist to phorbol ester tumor promoter TPA.
Biochem/physiol Actions: Bryostatin 3 is a potent protein kinase C activator with a Ki of 2.75 nM, and an antagonist to phorbol ester tumor promoter TPA. Bryostatin 3 is isolated from the bryozoan Bugula neritina.
Packaging: 10 μg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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