Febuxostat

SIGMA/SML1285 - 98.5-102.0%

Synonym: 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid; Adenuric; Atenuri; Uloric

CAS Number: 144060-53-7
Empirical Formula (Hill Notation): C₁₆H₁₆N₂O₃S
Molecular Weight: 316.37
MDL Number: MFCD00871598
Linear Formula: C₁₆H₁₆N₂O₃S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1285-1G	1 g	$228.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	98.5-102.0%
form	powder
InChI	1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
InChI key	BQSJTQLCZDPROO-UHFFFAOYSA-N
Quality Level	200
SMILES string	CC(C)COC1=C(C#N)C=C(C2=NC(C)=C(C(O)=O)S2)C=C1
storage temp.	2-8°C

Biochem/physiol Actions:	Febuxostat is a potent non-purine xanithine oxidase inhibitor.
Biochem/physiol Actions:	Febuxostat is a potent non-purine xanithine oxidase inhibitor. Febuxostat is used in urate lowering therapies (ULTs) for the treatment of gout.
Disclaimer:	Freely soluble in N,N-dimethyl formamide, Soluble in dimethyl sulfoxide, sparingly soluble in ethanol or trichloromethane, slightly soluble in methanol, practically insoluble in water
General description:	Febuxostat is a potent, non-purine compound, which inhibits the expression of cytokines/chemokines. It has also been reported to inhibit LPS-induced TNF-α, VCAM-1, MMP9 and MCP-1 expression.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98.5-102.0%
Storage Temp.	2-8°C
UNSPSC	51111800

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