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ML309 hydrochloride

SIGMA/SML1298 - ≥98% (HPLC)

Synonym: N-[2-(Cyclopentylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-1H-benzimidazole-1-acetamide hydrochloride

CAS Number: 1355327-02-4
Empirical Formula (Hill Notation): C29H29FN4O2 · HCl
Molecular Weight: 521.03
Linear Formula: C29H29FN4O2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1298-5MG 5 mg
 $111.00
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45-SML1298-25MG 25 mg
 $295.00
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: ML309 is a potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) (R132H and R132C) that binds reversibly the enzyme. ML309 inhibits production of neomorphic 2-hydroxyglutarate in glioblastoma cell line.
Biochem/physiol Actions: ML309 is a potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) (R132H and R132C).
Packaging: 5, 25 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P310 + P330
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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