TC-2153
SIGMA/SML1299 - ≥95% (HPLC)
Synonym: 8-
CAS Number: 1381769-23-8
Empirical Formula (Hill Notation): C7H4F3NS5 · HCl
Molecular Weight: 355.89
Linear Formula: C7H4F3NS5 · HCl
Product Type: Chemical
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| assay | ≥95% (HPLC) |
| color | white to beige |
| form | powder |
| Quality Level | 100  |
| shipped in | wet ice |
| solubility | DMSO: 5 mg/mL, clear |
| storage temp. | −20°C |
| Biochem/physiol Actions: | TC-2153 is a potent inhibitor of STEP (STriatal-Enriched protein tyrosine Phosphatase) that forms a reversible covalent bond with the catalytic cysteine in STEP. TC-2153 increases tyrosine phosphorylation of STEP substrates ERK1/2, Pyk2, and GluN2B in cell cultures. TC-2153 improves cognitive function in transgenic AD mice. |
| Biochem/physiol Actions: | TC-2153 is a potent inhibitor of STEP (STriatal-Enriched protein tyrosine Phosphatase). |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |