Advanced Search



Rubone

SIGMA/SML1311 - ≥98% (HPLC)

Synonym: (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one; 2′-Hydroxy-2,4,4′,5,6′-pentamethoxychalcone

CAS Number: 73694-15-2
Empirical Formula (Hill Notation): C20H22O7
Molecular Weight: 374.38
Linear Formula: C20H22O7
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1311-5MG 5 mg
 $69.50
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color yellow to orange
form powder
InChI 1S/C20H22O7/c1-23-13-9-15(22)20(19(10-13)27-5)14(21)7-6-12-8-17(25-3)18(26-4)11-16(12)24-2/h6-11,22H,1-5H3/b7-6+
InChI key VHCQVGQULWFQTM-VOTSOKGWSA-N
Quality Level 100 
SMILES string O(C)c1c(cc(c(c1)OC)C=CC(=O)c2c(cc(cc2O)OC)OC)OC
solubility DMSO: 2 mg/mL, clear (warmed)
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: Rubone has strong anticancer activity. Rubone and paclitaxel (PTX) combination therapy retarded cancer cell growth, migration and cancer stem-like cells (CSC) population growth.
Biochem/physiol Actions: Rubone is a miR34a modulator that specifically restores miR34a in hepatocellular carcinoma cells with wild-type or mutated p53. Rubone potently inhibits growth of hepatocellular carcinoma in a mouse xenograft model. Rubone does not effect the growth of nontumorigenic human hepatocytes.
Biochem/physiol Actions: Rubone is a miR34a modulator that specifically restores miR34a in hepatocellular carcinoma cells.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top