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HS-72

SIGMA/SML1325 - ≥98% (HPLC)

Synonym: (S)-N-(1-propyl-1H-benzimidazol-2-yl)-1-(2-pyrazinyl)-3-Piperidinecarboxamide

Empirical Formula (Hill Notation): C20H24N6O
Molecular Weight: 364.44
Linear Formula: C20H24N6O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1325-5MG 5 mg
 $161.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
solubility DMSO: 5 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: HS-72 is a cell permeable, highly selective allosteric inhibitor of inducible Hsp70 (Hsp70i) over constitutively active Hsc70. HS-72 inhibits cancer cell proliferation and promotes a survival in a HER2+ mouse model of breast cancer.
Biochem/physiol Actions: HS-72 is a cell permeable, highly selective allosteric inhibitor of inducible Hsp70 (Hsp70i).
Biochem/physiol Actions: HS-72 is also termed as ((S)-N-(1-propyl-1H-benzo[d]imidazol-2-yl)-1-(pyrazin-2-yl)piperidine-3-carboxamide). It is considered as a powerful anti-dengue virus (DENV) therapeutic agent. It displays anti-DENV activity in monocyte and liver cell lines. HS-72 stimulates the accumulation of cellular proteins.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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