STF-118804
SIGMA/SML1348 - ≥98% (HPLC)
Synonym: 4-
CAS Number: 894187-61-2
Empirical Formula (Hill Notation): C25H23N3O4S
Molecular Weight: 461.53
MDL Number: MFCD14918065
Linear Formula: C25H23N3O4S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C25H23N3O4S/c1-17-5-11 |
InChI key | DLFCEZOMHBPDGI-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | O=C(C1=CC=C(C2=NC(CS(=O)( |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | STF-118804 displays pancreatic ductal adenocarcinoma (PDAC) growth reducing potential in combination with chemotherapeutic drugs. |
Biochem/physiol Actions: | STF-118804 is a highly specific and potent NAMPT (nicotinamide phosphoribosyl transferase) inhibitor that reduces the viability of most B-ALL cell lines. STF 118804 induces leukemia cell apoptosis including leukemia initiating (stem) cells. STF 118804 improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 51111800 |