ML351
SIGMA/SML1353 - ≥98% (HPLC)
Synonym: 5-
CAS Number: 847163-28-4
Empirical Formula (Hill Notation): C15H11N3O
Molecular Weight: 249.27
MDL Number: MFCD04183120
Linear Formula: C15H11N3O
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C15H11N3O/c1-17-15-13( |
InChI key | DYXYXTDIFMDJIR-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | CNC1=C(C#N)N=C(O1)C2=C3C( |
solubility | DMSO: 10 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | ML351 is a cell penetrant, selective and highly potent human lipoxygenase-12/15 (15-Lipoxygenase-1, 12/15-LOX) inhibitor that exhibits protective effects against oxidative glutamate toxicity in mouse neuronal HT22 cells. ML351 reduces infarct size in a mouse model of ischemic stroke. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |