ML351

SIGMA/SML1353 - ≥98% (HPLC)

Synonym: 5-(Methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile; CID 664510; ML 351; SID 104223766

CAS Number: 847163-28-4
Empirical Formula (Hill Notation): C₁₅H₁₁N₃O
Molecular Weight: 249.27
MDL Number: MFCD04183120
Linear Formula: C₁₅H₁₁N₃O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1353-5MG	5 mg	$257.00 1/EA	Add To Favorites
45-SML1353-25MG	25 mg	$1020.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C15H11N3O/c1-17-15-13(9-16)18-14(19-15)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,17H,1H3
InChI key	DYXYXTDIFMDJIR-UHFFFAOYSA-N
Quality Level	100
SMILES string	CNC1=C(C#N)N=C(O1)C2=C3C(C=CC=C3)=CC=C2
solubility	DMSO: 10 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	ML351 is a cell penetrant, selective and highly potent human lipoxygenase-12/15 (15-Lipoxygenase-1, 12/15-LOX) inhibitor that exhibits protective effects against oxidative glutamate toxicity in mouse neuronal HT22 cells. ML351 reduces infarct size in a mouse model of ischemic stroke.
Biochem/physiol Actions:	ML351 is a cell penetrant, selective and highly potent human lipoxygenase-12/15 (15-Lipoxygenase-1, 12/15-LOX) inhibitor.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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