Cariporide
SIGMA/SML1360 - ≥98% (HPLC)
Synonym: HOE-642; N-
CAS Number: 159138-80-4
Empirical Formula (Hill Notation): C12H17N3O3S
Molecular Weight: 283.35
Linear Formula: C12H17N3O3S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C12H17N3O3S/c1-7(2)9-5 |
InChI key | IWXNYAIICFKCTM-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | NC(NC(C1=CC(S(C)(=O)=O)=C |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Cariporide is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. Cariporide has shown cardioprotective and antiarrhythmic effects, and has recently been investigated for anticancer activity. |
Biochem/physiol Actions: | Cariporide, a sodium-hydrogen exchange inhibitor can decrease the liberation of myoglobin at the time of ischemia/reperfusion and reduces the liberation of NE (norepinephrine) during ischemia. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |