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CVT-10216

SIGMA/SML1366 - ≥98% (HPLC)

Synonym: 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]-benzoic acid; 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic acid; CVT 10216; GS 455534

CAS Number: 1005334-57-5
Empirical Formula (Hill Notation): C24H19NO7S
Molecular Weight: 465.48
MDL Number: MFCD18072197
Linear Formula: C24H19NO7S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1366-5MG 5 mg
 $156.00
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45-SML1366-25MG 25 mg
 $618.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C24H19NO7S/c1-33(29,30)25-18-7-5-16(6-8-18)21-14-32-22-12-19(9-10-20(22)23(21)26)31-13-15-3-2-4-17(11-15)24(27)28/h2-12,14,25H,13H2,1H3,(H,27,28)
InChI key YYOOFJZTRCPVFD-UHFFFAOYSA-N
Quality Level 100 
SMILES string O=C(O)C1=CC(COC2=CC=C3C(OC=C(C4=CC=C(NS(C)(=O)=O)C=C4)C3=O)=C2)=CC=C1
solubility DMSO: 10 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: CVT-10216 is a selective reversible inhibitor of aldehyde dehydrogenase-2 (ALDH-2), thereby inhibiting dopamine synthesis. CVT-10216 is active in suppressing alcohol and cocaine use, and anxiety.
Biochem/physiol Actions: CVT-10216 is a selective reversible inhibitor of aldehyde dehydrogenase-2.
Biochem/physiol Actions: CVT-10216 possesses unequivocal anxiolytic properties. It will not affect the suppression of locomotor activity by mCPP (m-chlorophenylpiperazine).
General description: CVT-10216 is a 5-HT2c agonist.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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