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Calindol hydrochloride

SIGMA/SML1386 - ≥98% (HPLC)

Synonym: (R)-2-[[[1-(1-Naphthyl)ethyl]amino]methyl]-1H-indole hydrochloride; N-[(1R)-1-(1-naphthalenyl)ethyl]-1H-Indole-2-methanamine hydrochloride

CAS Number: 729610-18-8
Empirical Formula (Hill Notation): C21H20N2 · HCl
Molecular Weight: 336.86
MDL Number: MFCD18382212
Linear Formula: C21H20N2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1386-5MG 5 mg
 $257.00
1/EA		 Add To Favorites
45-SML1386-25MG 25 mg
 $724.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C21H20N2.ClH/c1-15(19-11-6-9-16-7-2-4-10-20(16)19)22-14-18-13-17-8-3-5-12-21(17)23-18;/h2-13,15,22-23H,14H2,1H3;1H/t15-;/m1./s1
InChI key KFILKQPBQZIRST-XFULWGLBSA-N
Quality Level 100 
SMILES string [H]Cl.C[C@@H](NCC1=CC2=C(N1)C=CC=C2)C3=CC=CC4=C3C=CC=C4
solubility DMSO: 10 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: Calcimimetic; Ca Sensing Receptor (CaSR) Agonist
Biochem/physiol Actions: Calindol is a calcimimetic Ca Sensing Receptor (CaSR) agonist. It is a positive allosteric modulator (PAM) with an EC50 value of 1 μM and a maximum stimulation of 130% of the 10mM Ca2+ activation in triggering PI hydrolysis.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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