Olmesartan

SIGMA/SML1394 - ≥98% (HPLC)

Synonym: 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid; Olmesartan acid

CAS Number: 144689-24-7
Empirical Formula (Hill Notation): C₂₄H₂₆N₆O₃
Molecular Weight: 446.50
MDL Number: MFCD09749896
Linear Formula: C₂₄H₂₆N₆O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1394-50MG	50 mg	$161.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)
InChI key	VTRAEEWXHOVJFV-UHFFFAOYSA-N
Quality Level	100
SMILES string	OC(C)(C)C1=C(C(O)=O)N(CC2=CC=C(C3=C(C4=NNN=N4)C=CC=C3)C=C2)C(CCC)=N1
solubility	DMSO: 20 mg/mL, clear
storage temp.	2-8°C

Application:	Olmesartan has been used as an angiotensin II receptor 1 (AT1) receptor inhibitor to study the effect of angiotensin II type 1 receptor interactions in the regulation of renal afferent arterioles in angiotensin II-dependent hypertension.
Biochem/physiol Actions:	Olmesartan is an Angiotensin II Type I receptor blocker.
Biochem/physiol Actions:	Olmesartan is an Angiotensin II Type I receptor blocker. Olmesartan is the active form of the antihypertensive drug olmesartan medoxomil.
Biochem/physiol Actions:	Olmesartan possesses anti-inflammatory and anti-oxidative stress properties. It protects neuronal cells against oligomerized amyloid β (Aβ)-induced cellular senescence.
Packaging:	50 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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