MS37452

SIGMA/SML1405 - ≥98% (HPLC)

Synonym: 1-(2,3-Dimethoxybenzoyl)-4-[(3-methylphenoxy)acetyl]-piperazine (9CI); 1-[4-(2,3-Dimethoxybenzoyl)-1-piperazinyl]-2-(3-methylphenoxy)-ethanonemethylphenoxy)acetyl]-piperazine (9CI)

CAS Number: 423748-02-1
Empirical Formula (Hill Notation): C₂₂H₂₆N₂O₅
Molecular Weight: 398.45
MDL Number: MFCD03134667
Linear Formula: C₂₂H₂₆N₂O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1405-25MG	25 mg	$484.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C22H26N2O5/c1-16-6-4-7-17(14-16)29-15-20(25)23-10-12-24(13-11-23)22(26)18-8-5-9-19(27-2)21(18)28-3/h4-9,14H,10-13,15H2,1-3H3
InChI key	LUMCNRKHZRYQOV-UHFFFAOYSA-N
Quality Level	100
shipped in	wet ice
SMILES string	O=C(COC1=CC(C)=CC=C1)N2CCN(C(C3=CC=CC(OC)=C3OC)=O)CC2
solubility	DMSO: 20 mg/mL, clear
storage condition	desiccated
storage temp.	−20°C

Biochem/physiol Actions:	MS37452 is a selective Chromobox homolog 7 (CBX7) modulator that disrupts CBX7ChD binding to H3K27me3. MS37452 inhibits CBX7 binding to INK4/ARF gene locus, and induces decline of p14/ARF and p16/INK4a in human PC3 cells.
Biochem/physiol Actions:	MS37452 is a selective Chromobox homolog 7 (CBX7) modulator.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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