FSL-1

SIGMA/SML1420 - ≥80% (HPLC)

Synonym: (R,S)-Pam2Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH; Fibroblast-stimulating Lipopeptide; Pam2CGDPKHPKSF; S-[2,3-Bis[(1-Oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-a-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine

CAS Number: 322455-70-9
Empirical Formula (Hill Notation): C₈₄H₁₄₀N₁₄O₁₈S
Molecular Weight: 1666.16
Linear Formula: C₈₄H₁₄₀N₁₄O₁₈S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1420-100UG	100 µg	$336.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥80% (HPLC)
color	white to off-white
form	powder
Quality Level	100
solubility	H₂O: soluble
storage temp.	−20°C

Biochem/physiol Actions:	FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB.
Biochem/physiol Actions:	FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein LP44 of Mycoplasma salivarium. FSL-1 showed higher stimulatory activity than MALP-2 in its ability to induce TNF-α production in macrophages and NF-κB in TLR2/TLR6 transfected HEK293 cells.
Biochem/physiol Actions:	FSL-1 is a bacterial-derived toll-like receptor 2/6 agonist. It is capable of increasing resistance to herpes simplex virus type 2 (HSV-2) infection.
Other Notes:	Air sensitive
Preparation Note:	Reconstitute in endotoxin-free water.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥80% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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