PHCCC

SIGMA/SML1432 - ≥97% (HPLC)

Synonym: 7,7a-Dihydro-7-(hydroxyimino)-N-phenyl-benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide; N-Phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide

CAS Number: 179068-02-1
Empirical Formula (Hill Notation): C₁₇H₁₄N₂O₃
Molecular Weight: 294.30
Linear Formula: C₁₇H₁₄N₂O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1432-25MG	25 mg	$283.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
color	white to beige
form	powder
InChI	1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,21H,10H2,(H,18,20)/b19-15+
InChI key	FPXPIEZPAXSELW-XDJHFCHBSA-N
Quality Level	100
SMILES string	O=C(NC1=CC=CC=C1)C2(C/3C2)OC4=C(C=CC=C4)C3=N/O
solubility	DMSO: 10 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	PHCCC is a positive allosteric modulator (PAM) at the mGluR4 subtype that exhibits anxiolytic and anti-Parkinsonian effects in animal models. PHCCC is a potent group I metabotropic glutamate receptor antagonist.
Biochem/physiol Actions:	PHCCC is a positive allosteric modulator (PAM) at the mGluR4 subtype. PHCCC is a potent group I metabotropic glutamate receptor antagonist.
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P301 + P312 + P330
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352202

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