Isobavachalcone
SIGMA/SML1450 - ≥98% (HPCE)
Synonym: (2E)
CAS Number: 20784-50-3
Empirical Formula (Hill Notation): C20H20O4
Molecular Weight: 324.37
MDL Number: MFCD00902090
Linear Formula: C20H20O4
Product Type: Chemical
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1450-25MG.
This image depicts SML1450-25MG.
| assay | ≥98% (HPCE) |
| color | white to beige |
| form | powder |
| InChI | 1S/C20H20O4/c1-13(2)3-9-1 |
| InChI key | DUWPGRAKHMEPCM-IZZDOVSWSA |
| Quality Level | 100  |
| SMILES string | OC1=C(CC=C(C)C)C(O)=C(C(/ |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage condition | desiccated |
| protect from light | |
| storage temp. | −20°C |
| Biochem/physiol Actions: | Isobavachalcone is a chalcone isolated from multipurpose medical plant Psoralea corylifolia that inhibits LPS-induced ICAM-1 expression and leukocyte adhesion to brain endothelial cells. It appears that isobavachalcone modulates both MyD88-dependent and TRIF-dependent signaling of toll-like receptor 4 (TLR4). Isobavachalcone significantly inhibits both oligomerization and fibrillization of Aβ42. Isobavachalcone exhibits a wide spectrum of biological activities including antioxidative, antiplatelet, antimicrobial, anti-inflammatory, antitumor, and neuroprotective. |
| Biochem/physiol Actions: | Isobavachalcone is a chalcone isolated from multipurpose medical plant Psoralea corylifolia that inhibits LPS-induced ICAM-1 expression and leukocyte adhesion to brain endothelial cells. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPCE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |