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MI192 hydrochloride

SIGMA/SML1451 - ≥98% (HPLC)

Synonym: N-(2-Aminophenyl)-4-[(3,4-dihydro-4-methylene-1-oxo-2(1H)-isoquinolinyl)methyl]-benzamide hydrochloride; MI-192 hydrochloride

CAS Number: 1415340-63-4 (free base)
Empirical Formula (Hill Notation): C24H21N3O2 · xHCl
Molecular Weight: 383.44 (free base basis)
Linear Formula: C24H21N3O2 · xHCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1451-5MG 5 mg
 $104.00
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assay ≥98% (HPLC)
color white to light brown
form powder
InChI 1S/C24H21N3O2/c1-16-14-27(24(29)20-7-3-2-6-19(16)20)15-17-10-12-18(13-11-17)23(28)26-22-9-5-4-8-21(22)25/h2-13H,1,14-15,25H2,(H,26,28)
InChI key GTLTXEIKQVWSRF-UHFFFAOYSA-N
Quality Level 100 
SMILES string C=C(CN1CC2=CC=C(C(NC3=CC=CC=C3N)=O)C=C2)C4=CC=CC=C4C1=O
solubility DMSO: 5 mg/mL, clear (warmed)
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: MI192 is a potent and selective histone deacetylase 3 (HDAc 3) inhibitor that inhibits IL-6 production in peripheral blood mononuclear cells (PBMCs) from rheumatoid arthritis (RA) but not healthy PBMCs.
Biochem/physiol Actions: MI192 is a potent and selective histone deacetylase 3 (HDAc 3) inhibitor.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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