Ibufenac
SIGMA/SML1452 - ≥95% (HPLC)
Synonym: 4-
CAS Number: 1553-60-2
Empirical Formula (Hill Notation): C12H16O2
Molecular Weight: 192.25
EC Number: 216-302-2
MDL Number: MFCD00864374
Linear Formula: C12H16O2
Product Type: Chemical
assay | ≥95% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C12H16O2/c1-9(2)7-10-3 |
InChI key | CYWFCPPBTWOZSF-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | OC(CC1=CC=C(CC(C)C)C=C1)= |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-1 and -2 activity with IC50 values of 17.4 and 13.1 μM, respectively and > 40 μM for 5-LOX. It has been used in studies of drug-induced hepatotoxicity. |
Packaging: | 10, 50 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |