SAMS Peptide trifluoroacetate salt

SIGMA/SML1460 - ≥95% (HPLC)

Synonym: HMRSAMSGLHLVKRR trifluoroacetate salt; His-Met-Arg-Ser-Ala-Met-Ser-Gly-Leu-His-Leu-Val-Lys-Arg-Arg-OH trifluoroacetate salt; L-Histidyl-L-methionyl-L-arginyl-L-seryl-L-alanyl-L-methionyl-L-seryl-glycyl-L-leucyl-L-histidyl-L-leucyl-L-valyl-L-lysyl-L-arginyl-L-arginine trifluoroacetate salt

CAS Number: 125911-68-4 (free base)
Empirical Formula (Hill Notation): C₇₄H₁₃₁N₂₉O₁₈S₂ · xC₂HF₃O₂
Molecular Weight: 1779.15 (free base basis)
Linear Formula: C₇₄H₁₃₁N₂₉O₁₈S₂ · xC₂HF₃O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1460-1MG	1 mg	$180.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
color	white to off-white
form	powder
InChI	1S/C74H131N29O18S2/c1-38(2)27-51(66(115)100-53(30-43-32-84-37-90-43)67(116)99-52(28-39(3)4)68(117)103-57(40(5)6)70(119)97-45(15-10-11-21-75)61(110)95-46(16-12-22-85-72(77)78)62(111)98-50(71(120)121)18-14-24-87-74(81)82)92-56(106)33-88-60(109)54(34-104)101-65(114)48(19-25-122-8)93-58(107)41(7)91-69(118)55(35-105)102-63(112)47(17-13-23-86-73(79)80)96-64(113)49(20-26-123-9)94-59(108)44(76)29-42-31-83-36-89-42/h31-32,36-41,44-55,57,104-105H,10-30,33-35,75-76H2,1-9H3,(H,83,89)(H,84,90)(H,88,109)(H,91,118)(H,92,106)(H,93,107)(H,94,108)(H,95,110)(H,96,113)(H,97,119)(H,98,111)(H,99,116)(H,100,115)(H,101,114)(H,102,112)(H,103,117)(H,120,121)(H4,77,78,85)(H4,79,80,86)(H4,81,82,87)/t41-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,57-/m0/s1
InChI key	YJAHUEAICBOBTC-CSVPVIMBSA-N
Quality Level	100
SMILES string	S(CC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2nc[nH]c2)CCSC)CCCNC(=N)N)CO)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(
storage temp.	−20°C

Biochem/physiol Actions:	SAMS Peptide is a synthetic substrate selective for AMP-activated protein kinase (AMPK). Its sequence is based on acetyl-CoA carboxylase, which is phosphorylated exclusively by the AMPK, but with serine (Ser)-79 replaced by alanine SAMS peptide is more specific for AMPK than acetyl-CoA carboxylase itself.
Biochem/physiol Actions:	Substrate selecive for AMP-activated protein kinase (AMPK)
General description:	SAMS Peptide trifluoroacetate salt is a peptide having a putative AMPK phosphorylation site (Ser568) of carbohydrate-responsive element-binding protein (ChREBP) and a peptide containing a cAMP-dependent protein kinase (PKA) phosphorylation site (Thr666).
Packaging:	1 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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