ASP7663
SIGMA/SML1467 - ≥98% (HPLC)
Synonym: (2E)
CAS Number: 1190217-35-6
Empirical Formula (Hill Notation): C14H14FNO3
Molecular Weight: 263.26
Linear Formula: C14H14FNO3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | light orange to dark orange |
form | powder |
InChI | 1S/C14H14FNO3/c1-8(2)7-16 |
InChI key | RCVZUIGCNAAMIC-UXBLZVDNSA |
Quality Level | 100 |
SMILES string | CC(C)CN(C1=C(F)C=CC=C1/C2 |
solubility | DMSO: 25 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC50 values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |