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Dienogest

SIGMA/SML1468 - ≥98% (HPLC)

Synonym: (17a)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile; 17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile; 17-cyanomethyl-17-hydroxy-estra-4,9-dien-3-one

CAS Number: 65928-58-7
Empirical Formula (Hill Notation): C20H25NO2
Molecular Weight: 311.42
MDL Number: MFCD00868356
Linear Formula: C20H25NO2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1468-10MG 10 mg
 $119.00
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45-SML1468-50MG 50 mg
 $365.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1468-50MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1
InChI key AZFLJNIPTRTECV-FUMNGEBKSA-N
optical activity [α]/D -305 to -325°, c = 1 in dichloromethane
Quality Level 100 
SMILES string O[C@@]1(CC#N)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3CC[C@@]21C)=O
solubility DMSO: 5 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: Dienogest is a fourth-generation progestin, an orally active synthetic progestogen with approximately 10% of the relative affinity of progesterone, but has a very potent progestagenic effect in the endometrium with some antiandrogenic activity and without any androgenic, glucocorticoid or mineralocorticoid effects. It has been used alone or in combination as a contraceptive and to treat uterine fibroids. Dienogest inhibits ovulation primarily through peripheral action rather than by central action on gonadotrophin secretion.
Biochem/physiol Actions: Dienogest is an orally active synthetic progestogen
Biochem/physiol Actions: Dienogest is used to treat endometriosis. It might also help to decrease the levels of plasma estradiol by stimulating cell death of granulosa cells in the ovary.
Packaging: 10, 50 mg in glass bottle
Symbol GHS08  GHS08
Signal word Warning
Hazard statements H361
Precautionary statements P280
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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