Chlorcyclizine
SIGMA/SML1473 - ≥98% (HPLC)
Synonym: 1-
CAS Number: 82-93-9
Empirical Formula (Hill Notation): C18H21ClN2
Molecular Weight: 300.83
MDL Number: MFCD00056036
Linear Formula: C18H21ClN2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | yellow to orange |
form | oil |
InChI | 1S/C18H21ClN2/c1-20-11-13 |
InChI key | WFNAKBGANONZEQ-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | ClC(C=C1)=CC=C1C(N2CCN(C) |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Chlorcyclizine is a first-generation antihistamine being studied as a potential treatment for hepatitis C. Chlorcyclizine is believed to inhibit an early stage of HCV infection, targeting viral entry into host cells. Chlorcyclizine inihbited the entry of cell culture-produced HCV with an IC50 value 2.3 nM. In human hepatoma cells and primary human hepatocytes, Chlorcyclizine showed a synergistic effect with other hepatitis C drugs such as ribavirin, interferon, telaprevir, boceprevir, sofosbuvir, daclatasvir, and cyclosporin A. |
RIDADR | UN 3077 9 / PGIII |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |