Synonym: Alclometasone Dipropanoate; Sch 22219; (7α,11β,16α)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione; 7α-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate); Alclometasone 17,21-dipropionate
CAS Number: 66734-13-2
Empirical Formula (Hill Notation): C28H37ClO7
Molecular Weight: 521.04
EC Number: 266-464-3
Linear Formula: C28H37ClO7
Product Type: Chemical
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| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C28H37ClO7/c1-6-22(33)35-14-21(32)28(36-23(34)7-2)15(3)10-18-24-19(29)12-16-11-17(30)8-9-26(16,4)25(24)20(31)13-27(18,28)5/h8-9,11,15,18-20,24-25,31H,6-7,10,12-14H2,1-5H3/t15-,18+,19-,20+,24-,25+,26+,27+,28+/m1/s1 |
| InChI key |
DJHCCTTVDRAMEH-DUUJBDRPSA-N |
| Quality Level |
100  |
| SMILES string |
Cl[C@H]1[C@@H]2[C@@H]([C@@]4(C(=CC(=O)C=C4)C1)C)[C@H](C[C@]3([C@H]2C[C@H]([C@]3(OC(=O)CC)C(=O)COC(=O)CC)C)C)O |
| solubility |
DMSO: 2 mg/mL, clear (warmed) |
| storage condition |
desiccated |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
Alclometasone dipropionate is a glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, immunosuppressive, antipruritic, and vasoconstrictive effects of natural glucocorticoids. |
| Packaging: |
10, 50 mg in glass bottle |
| Symbol |
GHS08 |
| Signal word |
Warning |
| Hazard statements |
H361d |
| Precautionary statements |
P280 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |