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Alclometasone dipropionate

SIGMA/SML1480 - ≥98% (HPLC)

Synonym: Alclometasone Dipropanoate; Sch 22219; (7α,11β,16α)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione; 7α-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate); Alclometasone 17,21-dipropionate

CAS Number: 66734-13-2
Empirical Formula (Hill Notation): C28H37ClO7
Molecular Weight: 521.04
EC Number: 266-464-3
Linear Formula: C28H37ClO7
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1480-50MG 50 mg
 $408.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C28H37ClO7/c1-6-22(33)35-14-21(32)28(36-23(34)7-2)15(3)10-18-24-19(29)12-16-11-17(30)8-9-26(16,4)25(24)20(31)13-27(18,28)5/h8-9,11,15,18-20,24-25,31H,6-7,10,12-14H2,1-5H3/t15-,18+,19-,20+,24-,25+,26+,27+,28+/m1/s1
InChI key DJHCCTTVDRAMEH-DUUJBDRPSA-N
Quality Level 100 
SMILES string Cl[C@H]1[C@@H]2[C@@H]([C@@]4(C(=CC(=O)C=C4)C1)C)[C@H](C[C@]3([C@H]2C[C@H]([C@]3(OC(=O)CC)C(=O)COC(=O)CC)C)C)O
solubility DMSO: 2 mg/mL, clear (warmed)
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: Alclometasone dipropionate is a glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, immunosuppressive, antipruritic, and vasoconstrictive effects of natural glucocorticoids.
Packaging: 10, 50 mg in glass bottle
Symbol GHS08  GHS08
Signal word Warning
Hazard statements H361d
Precautionary statements P280
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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