Ogerin negative control

SIGMA/SML1483 - ≥98% (HPLC)

Synonym: 3-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-benzenemethanol

CAS Number: 1125453-08-8
Empirical Formula (Hill Notation): C₁₇H₁₇N₅O
Molecular Weight: 307.35
Linear Formula: C₁₇H₁₇N₅O
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML1483-5MG	5 mg	$108.00 1/EA		Add To Favorites
45-SML1483-25MG	25 mg	$435.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22)
InChI key	RVKAHYFWSKSSQQ-UHFFFAOYSA-N
Quality Level	100
SMILES string	NC1=NC(C2=CC(CO)=CC=C2)=NC(NCC3=CC=CC=C3)=N1
solubility	DMSO: 20 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	Ogerin negative control is a structurally similar analog of ogerin (catalog no. SML1482). Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. The meta-analog is inactive and serves as a negative control.
Packaging:	5, 25 mg in glass bottle
Recommended products:	The positive allosteric modulator, ogerin, is available from Sigma. To learn more about and purchase ogerin, click here .

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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