FICZ

SIGMA/SML1489 - ≥95% (HPLC)

Synonym: 5,11-Dihydro-indolo[3,2-b]carbazole-6-carboxaldehyde; 6-Formylindolo[3,2-b]carbazole

CAS Number: 172922-91-7
Empirical Formula (Hill Notation): C₁₉H₁₂N₂O
Molecular Weight: 284.31
Linear Formula: C₁₉H₁₂N₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML1489-1MG	1 mg	$134.00 1/EA		Add To Favorites
45-SML1489-5MG	5 mg	$543.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
color	yellow
form	lyophilized powder
Quality Level	100
solubility	DMSO: 0.5 mg/mL, clear (warmed)
storage temp.	−20°C

Biochem/physiol Actions:	FICZ (6-formylindolo(3,2b)carbazole) being a photooxidation product of tryptophan, might serve as a chemical messenger of light.
Biochem/physiol Actions:	FICZ is a potent high affinity ligand of the aryl hydrocarbon receptor (AhR), which is a ligand-activated transcription factor that activates the expression of aromatic hydrocarbon metabolizing enzyme genes such as the CYP1A1 gene and has also been shown to have multiple additional roles in cell-cycle regulation, development and maturation of many tissues, control of inflammation, and immune response. FICZ is a photoproduct of tryptophan and is believed to be an endogenous AhR ligand. It is extremely potent, with a Kd value of 0.07 nM.
Packaging:	1, 5 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P301 + P312 + P330
Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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