Synonym: 4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid (2E)-2-[(4-methylphenyl)methylene]hydrazide; 4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid [1p-tolyl-meth-(E)-ylidene]-hydrazide; SRF
CAS Number: 1477482-50-0
Empirical Formula (Hill Notation): C16H18N4O
Molecular Weight: 282.34
Linear Formula: C16H18N4O
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
Quality Level |
100 |
solubility |
DMSO: 10 mg/mL, clear |
storage condition |
desiccated |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Suprafenacine is a cell permeable and potent microtubule destabilizing agent that induces cell cycle arrest in the G2/M phase and apoptotic cell death. Suprafenacine binds to microtubules at the colchicine-binding and inhibits polymerization. Suprafenacine is selective for cancer cells including drug-resistant cancer cells. Apparently, Suprafenacine bypasses the multidrug resistance transporter P-glycoprotein (PGP). |
Packaging: |
5, 25 mg in glass bottle |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |