Synonym: (E)-1-[4-(2-Oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one maleate; 1-(Pyrrolidinyl-1-carbonyl)-methyl-4-(3,4,5-trimethoxycinnamoyl)-piperazine-maleate
CAS Number: 26328-04-1
Empirical Formula (Hill Notation): C22H31N3O5 · C4H4O4
Molecular Weight: 533.57
MDL Number: MFCD01320526
Linear Formula: C22H31N3O5 · C4H4O4
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
InChI |
1S/C22H31N3O5.C4H4O4/c1-28-18-14-17(15-19(29-2)22(18)30-3)6-7-20(26)25-12-10-23(11-13-25)16-21(27)24-8-4-5-9-24;5-3(6)1-2-4(7)8/h6-7,14-15H,4-5,8-13,16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b7-6+;2-1- |
InChI key |
XSTJTOKYCAJVMJ-GVTSEVKNSA-N |
Quality Level |
100 |
SMILES string |
O=C(O)/C=CC(O)=O.O=C(N1CCN(CC(N2CCCC2)=O)CC1)/C=C/C3=CC(OC)=C(OC)C(OC)=C3 |
solubility |
H2O: 20 mg/mL, clear |
storage condition |
desiccated |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Cinepazide maleate is a vasodilator used clinically in China used in China for the treatment of cardiovascular and cerebrovascular diseases, and peripheral vascular diseases. Cinepazide maleate is thought to act as a potentiator of adenosine A2 receptors and has also been characterized as a calcium channel blocker. It was withdrawn for agranulocytosis in several countries. |
General description: |
Cinepazide maleate can be synthesized from ethyl chlorocarbonate activation and (E) 3,4,5-trimethoxycinnamylic acid. |
Packaging: |
50 mg in glass bottle |
Symbol |
GHS07 |
Signal word |
Warning |
Hazard statements |
H302 |
Precautionary statements |
P301 + P312 + P330 |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |