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Tegaserod maleate

SIGMA/SML1504 - ≥98% (HPLC)

Synonym: 2-[(5-Methoxy-1H-indol-3-yl)methylene]-N-pentyl-hydrazinecarboximidamide maleate

CAS Number: 189188-57-6
Empirical Formula (Hill Notation): C16H23N5O · C4H4O4
Molecular Weight: 417.46
MDL Number: MFCD09028009
Linear Formula: C16H23N5O · C4H4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1504-10MG 10 mg
 $120.00
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45-SML1504-50MG 50 mg
 $490.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C16H23N5O.C4H4O4/c1-3-4-5-8-18-16(17)21-20-11-12-10-19-15-7-6-13(22-2)9-14(12)15;5-3(6)1-2-4(7)8/h6-7,9-11,19H,3-5,8H2,1-2H3,(H3,17,18,21);1-2H,(H,5,6)(H,7,8)/b20-11+;2-1-
InChI key CPDDZSSEAVLMRY-FEQFWAPWSA-N
Quality Level 100 
SMILES string N=C(NCCCCC)N/N=C/C1=CNC2=C1C=C(OC)C=C2.OC(/C=CC(O)=O)=O
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Application: Tegaserod maleate has been used to study its cytotoxic effects on human astrocytes and to study its effects as an anti-glioblastoma agent.
Biochem/physiol Actions: It stimulates neurotransmitter release from enteric nerves and regularizes gastrointestinal function. Tegaserod has been used to treat irritable bowel syndrome associated with constipation and chronic constipation.
Biochem/physiol Actions: Tegaserod is a potent full agonist at serotonin 5-HT4 receptors with an EC50 of 7 nM.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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