C-DIM12

SIGMA/SML1508 - ≥98% (HPLC)

Synonym: 3,3′-[(4-Chlorophenyl)methylene]bis-1H-indole; 4-Chlorophenyl-3,3′-diindolylmethane; 4-Chlorophenyldi-3-indolylmethane

CAS Number: 178946-89-9
Empirical Formula (Hill Notation): C₂₃H₁₇N₂Cl
Molecular Weight: 356.85
Linear Formula: C₂₃H₁₇N₂Cl
Product Type: Chemical

assay	≥98% (HPLC)
color	, light orange to dark red
form	powder
InChI	1S/C23H17ClN2/c24-16-11-9-15(10-12-16)23(19-13-25-21-7-3-1-5-17(19)21)20-14-26-22-8-4-2-6-18(20)22/h1-14,23,25-26H
InChI key	LTLRXTDMXOFBDW-UHFFFAOYSA-N
Quality Level	100
SMILES string	ClC(C=C1)=CC=C1C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5
solubility	DMSO: 20 mg/mL, clear
storage condition	protect from light
storage temp.	2-8°C

Biochem/physiol Actions:	C-DIM12 is a potent and selective nuclear receptor Nurr1 (NR4A2) activator that activates Nurr1 in urothelial carcinoma cells and in pancreatic cells. C-DIM12 suppresses inflammatory signaling in microglia.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable