MK6-83
SIGMA/SML1509 - ≥98% (HPLC)
Synonym: 5-
CAS Number: 1062271-24-2
Empirical Formula (Hill Notation): C16H20N2O2S2
Molecular Weight: 336.47
Linear Formula: C16H20N2O2S2
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to brown |
| form | powder |
| InChI | 1S/C16H20N2O2S2/c1-13-9-1 |
| InChI key | IRGYSXZCDAWOOC-UHFFFAOYSA |
| Quality Level | 100  |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | MK6-83 is a potent activator of wild type and mutant variants F465L and F408D of TRPML1 channel. MK6-83 weakly activates TRPML mutants R403C or V446L. MK6-83 restores channel function and rescue disease associated abnormalities in mucolipidosis type IV (MLIV) patient cells. |
| Biochem/physiol Actions: | MK6-83 is known to stimulate caspase-3-dependent apoptosis. It can also decrease the viability of cells. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |