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Macelignan

SIGMA/SML1519 - ≥98% (HPLC)

Synonym: (+)-Anwulignan; 4-[(2S,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxy-phenol; Anwulignan

CAS Number: 107534-93-0
Empirical Formula (Hill Notation): C20H24O4
Molecular Weight: 328.40
MDL Number: MFCD09953803
Linear Formula: C20H24O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1519-5MG 5 mg
 $101.00
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This image depicts SML1519-5MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C20H24O4/c1-13(8-15-4-6-17(21)19(10-15)22-3)14(2)9-16-5-7-18-20(11-16)24-12-23-18/h4-7,10-11,13-14,21H,8-9,12H2,1-3H3/t13-,14+/m0/s1
InChI key QDDILOVMGWUNGD-UONOGXRCSA-N
Quality Level 100 
SMILES string OC1=C(OC)C=C(C[C@H](C)[C@H](C)CC2=CC=C(OCO3)C3=C2)C=C1
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: Macelignan is a neuroprotective lingan isolated from nutmeg (Myristica fragrans) that protects dopaminergic neurons from inflammatory degeneration. Apparently, the neuroprotective effect of macelignan is mediated by PPARγ activation and arginase-1 expression. Macelignan inhibits LPS induced production of NO as well and inflammatory cytokines including TNF and IL- 1β in primary cultures of microglia.
Biochem/physiol Actions: Macelignan is a neuroprotective lingan isolated from nutmeg.
General description: Macelignan is a naturally occurring compound that has scavenging effects on free-radicals and inhibits prostaglandin. It also exhibits antioxidant and anti-inflammatory effects.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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