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Eltoprazine hydrochloride

SIGMA/SML1526 - ≥98% (HPLC)

Synonym: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride

CAS Number: 98206-09-8
Empirical Formula (Hill Notation): C12H16N2O2 · HCl
Molecular Weight: 256.73
MDL Number: MFCD06245586
Linear Formula: C12H16N2O2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1526-25MG 25 mg
 $420.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;/h1-3,13H,4-9H2;1H
InChI key JFSOSUNPIXJCIX-UHFFFAOYSA-N
Quality Level 100 
SMILES string [H]Cl.C1(OCCO2)=C2C(N3CCNCC3)=CC=C1
solubility H2O: 10 mg/mL, clear
storage temp. room temp
Biochem/physiol Actions: Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. It has Ki values for 5-HT1A, 5-HT1B and 5-HT1C receptors of 40 nM and 52 nM, respectively.
Biochem/physiol Actions: Serotonin 5-HT1A/1B receptor agonist
General description: Eltoprazine, a serotonergic agent, possesses specific anti-aggressive (serenic) properties in various animal models without triggering sedation, motor disturbances, or muscle relaxation.
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352202

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