Erdosteine
SIGMA/SML1529 - ≥98% (HPLC)
Synonym: ({2-
CAS Number: 84611-23-4
Empirical Formula (Hill Notation): C8H11NO4S2
Molecular Weight: 249.31
MDL Number: MFCD00867664
Linear Formula: C8H11NO4S2
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C8H11NO4S2/c10-6(3-14- |
| InChI key | QGFORSXNKQLDNO-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | S1CCC(C1=O)NC(=O)CSCC(=O) |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| Application: | Erdosteine has been used as a mucolytic to study its protective effects on interleukin-1β-stimulated inflammation in rat chondrocytes in osteoarthritis models. |
| Biochem/physiol Actions: | Erdosteine is a mucolytic drug with expectorant and antitussive effects. |
| Biochem/physiol Actions: | Erdosteine is a mucolytic drug with expectorant and antitussive effects. Erdosteine is quickly metabolized in vivo to free thiols which act as free radical scavengers. Erdosteine has also been shown to have antioxidant activity through the activation of Nrf2-dependent antioxidant genes and inhibition of pro-inflammatory cytokines. |
| General description: | Erdosteine is a derivative of thiol, and is used in the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis.It consists of two blocked sulfhydryl groups, which are released following first-pass metabolism. |
| Packaging: | 50, 250 mg in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301 + P312 + P330 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |