Tipiracil hydrochloride
SIGMA/SML1552 - ≥98% (HPLC)
Synonym: 5-
CAS Number: 183204-72-0
Empirical Formula (Hill Notation): C9H11ClN4O2 · HCl
Molecular Weight: 279.12
MDL Number: MFCD01571384
Linear Formula: C9H11ClN4O2 · HCl
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C9H11ClN4O2.ClH/c10-7- |
| InChI key | KGHYQYACJRXCAT-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | [H]Cl.ClC1=C(CN2C(CCC2)=N |
| solubility | H2O: 5 mg/mL, clear (warmed) |
| storage condition | desiccated |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Tipiracil is an inhibitor of thymidine phosphorylase. |
| Biochem/physiol Actions: | Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory metastatic colorectal cancer. Tipiracil increases the bioavailability of trifluridine by blocking the enzyme that would otherwise protect the tumors by metabolizing trifluridine. |
| Packaging: | 10, 50 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |

