Tipiracil hydrochloride
SIGMA/SML1552 - ≥98% (HPLC)
Synonym: 5-
CAS Number: 183204-72-0
Empirical Formula (Hill Notation): C9H11ClN4O2 · HCl
Molecular Weight: 279.12
MDL Number: MFCD01571384
Linear Formula: C9H11ClN4O2 · HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C9H11ClN4O2.ClH/c10-7- |
InChI key | KGHYQYACJRXCAT-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | [H]Cl.ClC1=C(CN2C(CCC2)=N |
solubility | H2O: 5 mg/mL, clear (warmed) |
storage condition | desiccated |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory metastatic colorectal cancer. Tipiracil increases the bioavailability of trifluridine by blocking the enzyme that would otherwise protect the tumors by metabolizing trifluridine. |
Packaging: | 10, 50 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |