MS023 hydrochloride
SIGMA/SML1555 - ≥98% (HPLC)
Synonym: N1-
CAS Number: 1831110-54-3 (free base)
Empirical Formula (Hill Notation): C17H25N3O · xHCl
Molecular Weight: 287.40 (free base basis)
Linear Formula: C17H25N3O · xHCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to light brown |
form | powder |
InChI | 1S/C17H25N3O.ClH/c1-13(2) |
InChI key | IEZPALXFXHDDHI-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | CN(CCN)CC1=CNC=C1C2=CC=C( |
solubility | H2O: 20 mg/mL, clear |
storage condition | desiccated |
storage temp. | −20°C |
Biochem/physiol Actions: | MS023 is a potent and selective chemical probe for Type I protein arginine methyltransferases (PRMTs). MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues. MS023 is active in cells. For full characterization details, please visit the MS023 probe summary on the Structural Genomics Consortium (SGC) website. To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc |
Features and Benefits: | MS023 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC . |
Features and Benefits: | This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Other Notes: | MS023 has been expertly reviewed and recommended by the Chemical Probes Portal. For more information, please visit the MS023 probe summary on the Chemical Probes Portal website. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |