Azoramide

SIGMA/SML1560 - ≥98% (HPLC)

Synonym: N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]-butanamide; N-{2-[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]ethyl} butanamide

CAS Number: 932986-18-0
Empirical Formula (Hill Notation): C₁₅H₁₇ClN₂OS
Molecular Weight: 308.83
MDL Number: MFCD08009374
Linear Formula: C₁₅H₁₇ClN₂OS
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1560-10MG	10 mg	$93.90 1/EA	Add To Favorites
45-SML1560-50MG	50 mg	$381.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19)
InChI key	VYBFWKKCWTXCQX-UHFFFAOYSA-N
Quality Level	100
SMILES string	ClC1=CC=C(C2=NC(CCNC(CCC)=O)=CS2)C=C1
solubility	DMSO: 30 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:

Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It has dual activity: Azoramide improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones that protect cells against ER stress. Azoramide was shown to protect cells from death and dysfunction in multiple models of ER stress. It showed antidiabetic activity in two independent mouse models of obesity by improving insulin sensitivity and protecting pancreatic β cell function against ER stress.

Packaging:

10, 50 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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