Azoramide
SIGMA/SML1560 - ≥98% (HPLC)
Synonym: N-
CAS Number: 932986-18-0
Empirical Formula (Hill Notation): C15H17ClN2OS
Molecular Weight: 308.83
MDL Number: MFCD08009374
Linear Formula: C15H17ClN2OS
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C15H17ClN2OS/c1-2-3-14 |
InChI key | VYBFWKKCWTXCQX-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | ClC1=CC=C(C2=NC(CCNC(CCC) |
solubility | DMSO: 30 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It has dual activity: Azoramide improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones that protect cells against ER stress. Azoramide was shown to protect cells from death and dysfunction in multiple models of ER stress. It showed antidiabetic activity in two independent mouse models of obesity by improving insulin sensitivity and protecting pancreatic β cell function against ER stress. |
Packaging: | 10, 50 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |