A-196
SIGMA/SML1565 - ≥98% (HPLC)
Synonym: Cyclopentyl-
Empirical Formula (Hill Notation): C18H16Cl2N4
Molecular Weight: 359.25
MDL Number: MFCD29924807
Linear Formula: C18H16Cl2N4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to light brown |
form | powder |
InChI | 1S/C18H16Cl2N4/c19-15-9-1 |
InChI key | ABGOSOMRWSYAOB-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | ClC1=C(Cl)C=C(C(C2=CC=NC= |
solubility | DMSO: 5 mg/mL, clear (warmed) |
storage temp. | 2-8°C |
Biochem/physiol Actions: | A-196 is a potent and selective chemical inhibitor of SUV420H1 and SUV420H2 that inhibits the di- and trimethylation of H4K20me in multiple cell lines. For full characterization details, please visit the A-196 probe summary on the Structural Genomics Consortium (SGC) website. SGC2043 is the negative control for the active probe, A-196. To request a sample of the negative control from the SGC, click here . To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc |
Features and Benefits: | A-196 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC . |
Features and Benefits: | This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS06 |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P301 + P330 + P331 + P310 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |