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A-196

SIGMA/SML1565 - ≥98% (HPLC)

Synonym: Cyclopentyl-(6,7-dichloro-4-pyridin-4-yl-phthalazin-1-yl)-amine

CAS Number: 1982372-88-2
Empirical Formula (Hill Notation): C18H16Cl2N4
Molecular Weight: 359.25
MDL Number: MFCD29924807
Linear Formula: C18H16Cl2N4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1565-5MG 5 mg
 $131.00
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assay ≥98% (HPLC)
color white to light brown
form powder
InChI 1S/C18H16Cl2N4/c19-15-9-13-14(10-16(15)20)18(22-12-3-1-2-4-12)24-23-17(13)11-5-7-21-8-6-11/h5-10,12H,1-4H2,(H,22,24)
InChI key ABGOSOMRWSYAOB-UHFFFAOYSA-N
Quality Level 100 
SMILES string ClC1=C(Cl)C=C(C(C2=CC=NC=C2)=NN=C3NC4CCCC4)C3=C1
solubility DMSO: 5 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: A-196 is a potent and selective chemical inhibitor of SUV420H1 and SUV420H2 that inhibits the di- and trimethylation of H4K20me in multiple cell lines. For full characterization details, please visit the A-196 probe summary  on the Structural Genomics Consortium (SGC) website.

SGC2043 is the negative control for the active probe, A-196. To request a sample of the negative control from the SGC, click here .

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc 
Biochem/physiol Actions: A-196 is a potent and selective chemical inhibitor of SUV420H1 and SUV420H2.
Features and Benefits: A-196 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC .
Features and Benefits: This compound is a featured product for Gene Regulation research. Click here  to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging: 5, 25 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P330 + P331 + P310
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12171501

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