Tolrestat
SIGMA/SML1573 - ≥98% (HPLC)
Synonym: AY-27773; CID 53359; N-[[5 -
CAS Number: 82964-04-3
Empirical Formula (Hill Notation): C16H14F3NO3S
Molecular Weight: 357.35
Linear Formula: C16H14F3NO3S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C16H14F3NO3S/c1-20(8-1 |
InChI key | LUBHDINQXIHVLS-UHFFFAOYSA |
Quality Level | 100 ![]() |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Tolrestat is an orally active and potent aldose reductase inhibitor. Studies have also shown that it reduces RBC (red blood cells) sorbitol levels in rats. |
Biochem/physiol Actions: | Tolrestat is considered to be effective in treating the consequences of diabetes including neuropathy, nephropathy, retinopathy and esophageal motility and vibration perception. Tolrestat is also believed to have lesser or no toxic effects. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |