Synonym: 1-(p-Chloro-α-phenylbenzyl)-4-(p-tert-butylbenzyl)piperazine; 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)-diethylenediamine hydrochloride; 1-[(4-Chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-piperazine dihydrochloride; Buclina; Longifene; Posdel; UCB-4445; Vibazine; Vibazine hydrochloride
CAS Number: 129-74-8
Empirical Formula (Hill Notation): C28H33ClN2 · 2HCl
Molecular Weight: 505.95
MDL Number: MFCD00242700
Linear Formula: C28H33ClN2 · 2HCl
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24;;/h4-16,27H,17-21H2,1-3H3;2*1H |
| InChI key |
SDBHDSZKNVDKNU-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
[Cl-].[Cl-].Clc1ccc(cc1)C(N3CCN(CC3)Cc4ccc(cc4)C(C)(C)C)c2ccccc2.[H+].[H+] |
| solubility |
DMSO: 1 mg/mL, clear (warmed) |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
Buclizine is a piperazine antihistamine and anticholinergic that exerts its antiemetic and antimotion sickness effects. |
| Biochem/physiol Actions: |
Histamine H1 receptor antagonist |
| Packaging: |
50 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |
