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SRI-29574

SIGMA/SML1597 - ≥98% (HPLC)

Synonym: N-(2,2-Diphenylethyl)-2-(imidazo[1,2-a]pyridin-6-yl)quinazolin-4-amine

Empirical Formula (Hill Notation): C29H23N5
Molecular Weight: 441.53
Linear Formula: C29H23N5
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML1597-5MG 5 mg
$0.00
1/EA
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45-SML1597-25MG 25 mg
$0.00
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assay ≥98% (HPLC)
color white to light brown
form powder
Quality Level 100 
solubility DMSO: 2 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: DAT is crucial for regulating the levels of DA (dopamine). It is also responsible for the reuptake of 1-methyl-4-phenylpyridinium (MPP+), neurotoxin which mediates symptoms similar to Parkinson’s disease. Changes in DAT activity is associated with attention-deficit/hyperactivity and autism spectrum disorders.
Biochem/physiol Actions: SRI-29574 is a potent DAT (dopamine transporter) allosteric modulator that partially inhibits DAT uptake without affecting binding to DAT. SRI-29574 is a noncompetitive inhibitor of [3H]DA uptake. Also SRI-29574 partially inhibits SERT and NET uptake.
Packaging: 5, 25 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P330 + P331 + P310
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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