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VR23

SIGMA/SML1599 - ≥98% (HPLC)

Synonym: 7-Chloro-4-(4-(2,4-dinitrophenylsulfonyl)piperazin-1-yl)quinoline; 7-Chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]-quinoline; VR-23

CAS Number: 1624602-30-7
Empirical Formula (Hill Notation): C19H16ClN5O6S
Molecular Weight: 477.88
Linear Formula: C19H16ClN5O6S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML1599-5MG 5 mg
$134.00
1/EA
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45-SML1599-25MG 25 mg
$435.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: Proteasomes are responsible for the cleavage of peptides in an ATP/ubiquitin-dependent manner.
Biochem/physiol Actions: VR23 is a potent inhibitor of proteasome that primary targets β2 of the 20S proteasome catalytic subunit. VR23 selectively induces apoptosis to cancer cells via cyclin E–mediated centrosome amplification. VR23 exhibit little effect on noncancerous cells.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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