Rinvanil
SIGMA/SML1600 - ≥98% (HPLC)
Synonym: (9Z,12R)
CAS Number: 457643-60-6
Empirical Formula (Hill Notation): C26H43NO4
Molecular Weight: 433.62
Linear Formula: C26H43NO4
Product Type: Chemical
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| assay | ≥98% (HPLC) |
| color | colorless to yellow |
| form | oil |
| Quality Level | 100  |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Rinvanil is a Capsaicin analogue that potently activates transient receptor potential vanilloid 1 (TRPV1) channels. |
| Biochem/physiol Actions: | Rinvanil is a Capsaicin analogue that potently activates transient receptor potential vanilloid 1 (TRPV1) channels. Rinvanil induces neuroprotective mild hypothermia in ischemic brain injured mice through TRPV1 activation. Rinvanil exhibits potent anticancer activity in cancer cell lines including cervical (HeLa, CaSKi, ViBo) and leukemia (P388, J774, WEHI-3) cell lines. Rinvanil is not cytotoxic to normal lymphocytes. |
| Biochem/physiol Actions: | TRPV1 (transient receptor potential vanilloid 1) is a capsaicin receptor. It is strongly expressed in sensory neurons and participates in pain perception. In brain, it regulates neuronal function, motor behaviour and neuroinflammation. Capsaicin plays an important role in the activation of TRPV1. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |