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NSC59984

SIGMA/SML1601 - ≥98% (HPLC)

Synonym: (E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2yl)prop-2-en-1-one; 1-(4-Methyl-1-piperazinyl)-3-(5-nitro-2-furanyl)-2-propen-1-one; 1-Methyl-4-[3-(5-nitro-2-furanyl)-1-oxo-2-propenyl]-piperazine; CID 5356520; MLS000737358

CAS Number: 803647-40-7
Empirical Formula (Hill Notation): C12H15N3O4
Molecular Weight: 265.27
MDL Number: MFCD29905462
Linear Formula: C12H15N3O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1601-5MG 5 mg
 $108.00
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assay ≥98% (HPLC)
color yellow to brown
form powder
InChI 1S/C12H15N3O4/c1-13-6-8-14(9-7-13)11(16)4-2-10-3-5-12(19-10)15(17)18/h2-5H,6-9H2,1H3/b4-2+
InChI key QKTRIGNWBRHBFV-DUXPYHPUSA-N
Quality Level 100 
SMILES string CN1CCN(C(/C=C/C2=CC=C([N+]([O-])=O)O2)=O)CC1
solubility DMSO: 5 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: NSC59984 targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells. NSC59984 depletes a gain of function (GOF p53 mutants. NSC59984 is not cytotoxic against normal cells.
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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