NSC59984
SIGMA/SML1601 - ≥98% (HPLC)
Synonym: (E)
CAS Number: 803647-40-7
Empirical Formula (Hill Notation): C12H15N3O4
Molecular Weight: 265.27
MDL Number: MFCD29905462
Linear Formula: C12H15N3O4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | yellow to brown |
form | powder |
InChI | 1S/C12H15N3O4/c1-13-6-8-1 |
InChI key | QKTRIGNWBRHBFV-DUXPYHPUSA |
Quality Level | 100 |
SMILES string | CN1CCN(C(/C=C/C2=CC=C([N+ |
solubility | DMSO: 5 mg/mL, clear (warmed) |
storage temp. | 2-8°C |
Biochem/physiol Actions: | NSC59984 targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells. NSC59984 depletes a gain of function (GOF p53 mutants. NSC59984 is not cytotoxic against normal cells. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P302 + P352 - P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |