Oseltamivir phosphate
SIGMA/SML1606 - ≥98% (HPLC)
Synonym: GS4104; (3R,4R,5S)
CAS Number: 204255-11-8
Empirical Formula (Hill Notation): C16H28N2O4 ·H3PO4
Molecular Weight: 410.40
MDL Number: MFCD08059548
Linear Formula: C16H28N2O4 ·H3PO4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C16H28N2O4.H3O4P/c1-5- |
InChI key | PGZUMBJQJWIWGJ-ONAKXNSWSA |
optical activity | [α]/D -26 to -36°, c = 1 in H2O |
Quality Level | 100 |
SMILES string | OP(O)(O)=O.CCOC(=O)C1=C[C |
solubility | H2O: 30 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. Oseltamivir phosphate, an antiviral, is used clinically to treat influenza A and influenza B, and to prevent flu after exposure. Oseltamivir phosphate is hydrolyzed in the liver to its active form, oseltamivir carboxylate, which is an inhibitor of influenza viral neuraminidases essential for viral replication. Oseltamivir has a broad spectrum of activity against a range of influenza A and B subtypes with IC50 values for neuraminidases measured from less than 1 nM to approximately 30 nM, depending on the virus subtype. |
Packaging: | 100 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H317 - H319 - H412 |
Precautionary statements | P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |