Lesinurad

SIGMA/SML1607 - ≥98% (HPLC)

Synonym: 2-[[5-Bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic acid; RDEA 594

CAS Number: 878672-00-5
Empirical Formula (Hill Notation): C₁₇H₁₄BrN₃O₂S
Molecular Weight: 404.28
MDL Number: MFCD22572730
Linear Formula: C₁₇H₁₄BrN₃O₂S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1607-10MG	10 mg	$119.00 1/EA	Add To Favorites
45-SML1607-50MG	50 mg	$480.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23)
InChI key	FGQFOYHRJSUHMR-UHFFFAOYSA-N
Quality Level	100
SMILES string	BrC1=NN=C(SCC(O)=O)N1C2=C3C(C=CC=C3)=C(C4CC4)C=C2
solubility	DMSO: 25 mg/mL, clear
storage temp.	−20°C

Biochem/physiol Actions:	Lesinurad is a selective inhibitor of Urate transporter 1 (URAT1), a urate-anion exchanger which is responsible for the majority of uric acid reabsorption from the renal tubular lumen. Lesinurad thus reduces serum uric acid levels. Lesinurad has been approved for use in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout.
Biochem/physiol Actions:	Lesinurad is a selective inhibitor of Urate transporter 1 (URAT1).
Packaging:	10, 50 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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