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Lesinurad

SIGMA/SML1607 - ≥98% (HPLC)

Synonym: 2-[[5-Bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic acid; RDEA 594

CAS Number: 878672-00-5
Empirical Formula (Hill Notation): C17H14BrN3O2S
Molecular Weight: 404.28
MDL Number: MFCD22572730
Linear Formula: C17H14BrN3O2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1607-10MG 10 mg
 $108.00
1/EA		 Add To Favorites
45-SML1607-50MG 50 mg
 $435.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23)
InChI key FGQFOYHRJSUHMR-UHFFFAOYSA-N
Quality Level 100 
SMILES string BrC1=NN=C(SCC(O)=O)N1C2=C3C(C=CC=C3)=C(C4CC4)C=C2
solubility DMSO: 25 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: Lesinurad is a selective inhibitor of Urate transporter 1 (URAT1), a urate-anion exchanger which is responsible for the majority of uric acid reabsorption from the renal tubular lumen. Lesinurad thus reduces serum uric acid levels. Lesinurad has been approved for use in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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