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Besifloxacin hydrochloride

SIGMA/SML1608 - ≥98% (HPLC)

Synonym: 7-[-3-Aminoazepam-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

CAS Number: 1398566-43-2
Empirical Formula (Hill Notation): C19H21ClFN3O3 · HCl
Molecular Weight: 430.30
MDL Number: MFCD23712955
Linear Formula: C19H21ClFN3O3 · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML1608-10MG 10 mg
$93.90
1/EA
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45-SML1608-50MG 50 mg
$381.00
1/EA
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assay ≥98% (HPLC)
color white to light brown
form powder
Quality Level 100 
SMILES string [H]Cl.OC(C1=CN(C2CC2)C3=C(Cl)C(N4CCCCC(N)C4)=C(F)C=C3C1=O)=O
solubility DMSO: 2 mg/mL, clear (warmed)
storage condition desiccated
storage temp. −20°C
Biochem/physiol Actions: Besifloxacin is a broad spectrum fourth-generation fluoroquinolone antibiotic.
Biochem/physiol Actions: Besifloxacin is a broad spectrum fourth-generation fluoroquinolone antibiotic. Besifloxacin is effective against gram positive and negative, aerobic and anerobic bacteria. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Besifloxacin inhibits both DNA gyrase and topoisomerase IV at nearly equal concentrations. It is used clinically primarily in the treatment of bacterial conjunctivitis.
Biochem/physiol Actions: Besifloxacin stops the production of pro-inflammatory cytokines in vitro.
Packaging: 10, 50 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319 - H335
Precautionary statements P305 + P351 + P338
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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