Lafutidine

SIGMA/SML1611 - ≥98% (HPLC)

Synonym: (Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide; 2-[(2-Furanylmethyl)sulfinyl]-N-[(2Z)-4-[[4-(1-piperidinylmethyl)-2-pyridinyl]oxy]-2-buten-1-yl]-acetamide

CAS Number: 118288-08-7
Empirical Formula (Hill Notation): C₂₂H₂₉N₃O₄S
Molecular Weight: 431.55
MDL Number: MFCD00867520
Linear Formula: C₂₂H₂₉N₃O₄S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1611-10MG	10 mg	$103.00 1/EA	Add To Favorites
45-SML1611-50MG	50 mg	$195.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C22H29N3O4S/c26-21(18-30(27)17-20-7-6-14-28-20)23-9-2-5-13-29-22-15-19(8-10-24-22)16-25-11-3-1-4-12-25/h2,5-8,10,14-15H,1,3-4,9,11-13,16-18H2,(H,23,26)/b5-2-
InChI key	KMZQAVXSMUKBPD-DJWKRKHSSA-N
Quality Level	100
SMILES string	O=C(CS(CC1=CC=CO1)=O)NC/C=CCOC2=NC=CC(CN3CCCCC3)=C2
solubility	DMSO: 20 mg/mL, clear
storage temp.	−20°C

Biochem/physiol Actions:	Lafutidine is a second generation H2 histamine receptor antagonist.
Biochem/physiol Actions:	Lafutidine is a second generation H2 histamine receptor antagonist. Lafutidine has been used clinically to treat ulcers and gastro-esophageal reflux disease (GERD). Lafutidine has also been investigated as a treatment against peripheral neuropathy and for its protective stomach effects during cancer chemotherapies and long term ibuprofen use.
Packaging:	10, 50 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P301 + P312 + P330
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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