Rp-8-Br-cGMPS sodium salt
SIGMA/SML1614 - ≥98% (HPLC)
Synonym: Rp-8-Bromo-cGMPS sodium salt; Rp-8-Bromoguanosine- 3′, 5′- cyclic monophosphorothioate sodium salt
CAS Number: 208445-06-1
Empirical Formula (Hill Notation): C10H10BrN5O6PS · Na
Molecular Weight: 462.15
MDL Number: MFCD04037242
Linear Formula: C10H10BrN5O6PS · Na
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | lyophilized solid |
InChI | 1S/C10H11BrN5O6PS.Na/c11- |
InChI key | CHTSSROWUAICIL-GMKUFTCMSA |
Quality Level | 100 |
SMILES string | O=C1C2=C(N([C@@H]3O[C@H]( |
storage temp. | −20°C |
Biochem/physiol Actions: | Rp-8-bromo-cGMPS is a cell permeable cGMP analog that blocks cGMP-dependent protein kinase (cGK, G-kinase, Protein Kinase G, PKG). Rp-8-bromo-cGMPS is resistant to hydrolysis by phosphodiesterases and binds cGK without activating it, resulting in competitive inhibition. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |