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Rp-8-Br-cGMPS sodium salt

SIGMA/SML1614 - ≥98% (HPLC)

Synonym: Rp-8-Bromo-cGMPS sodium salt; Rp-8-Bromoguanosine- 3′, 5′- cyclic monophosphorothioate sodium salt

CAS Number: 208445-06-1
Empirical Formula (Hill Notation): C10H10BrN5O6PS · Na
Molecular Weight: 462.15
MDL Number: MFCD04037242
Linear Formula: C10H10BrN5O6PS · Na
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1614-1MG 1 mg
 $434.00
1/EA		 Add To Favorites
45-SML1614-5MG 5 mg
 $1430.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form lyophilized solid
InChI 1S/C10H11BrN5O6PS.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(21-8)1-20-23(19,24)22-5;/h2,4-5,8,17H,1H2,(H,19,24)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-,23-;/m1./s1
InChI key CHTSSROWUAICIL-GMKUFTCMSA-M
Quality Level 100 
SMILES string O=C1C2=C(N([C@@H]3O[C@H](CO[P@@](O4)([O-])=S)[C@@H]4[C@H]3O)C(Br)=N2)N=C(N)N1.[Na+]
storage temp. −20°C
Biochem/physiol Actions: Rp-8-bromo-cGMPS is a cell permeable cGMP analog that blocks cGMP-dependent protein kinase (cGK, G-kinase, Protein Kinase G, PKG). Rp-8-bromo-cGMPS is resistant to hydrolysis by phosphodiesterases and binds cGK without activating it, resulting in competitive inhibition.
Biochem/physiol Actions: Rp-8-bromo-cGMPS is a cell permeable cGMP analog.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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