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Garenoxacin mesylate monohydrate

SIGMA/SML1618 - ≥98% (HPLC)

Synonym: 1-Cyclopropyl-8-(difluoromethoxy)-7-[(1R)-2,3-dihydro-1-methyl-1H-isoindol-5-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid methane sulfonic acid salt monohydrate; BMS 284756 mesylate; Ganefloxacin mesylate; Garenfloxacin mesylate; T-3811 mesylate

CAS Number: 223652-90-2
Empirical Formula (Hill Notation): C23H20F2N2O4 · CH4O3S · H2O
Molecular Weight: 540.53
MDL Number: MFCD12031996
Linear Formula: C23H20F2N2O4 · CH4O3S · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1618-10MG 10 mg
 $119.00
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45-SML1618-50MG 50 mg
 $480.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1618-50MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C23H20F2N2O4.CH4O3S.H2O/c1-11-15-5-2-12(8-13(15)9-26-11)16-6-7-17-19(21(16)31-23(24)25)27(14-3-4-14)10-18(20(17)28)22(29)30;1-5(2,3)4;/h2,5-8,10-11,14,23,26H,3-4,9H2,1H3,(H,29,30);1H3,(H,2,3,4);1H2/t11-;;/m1../s1
InChI key IGTHEWGRXUAFKF-NVJADKKVSA-N
Quality Level 100 
SMILES string OC(C1=CN(C2CC2)C3=C(OC(F)F)C(C4=CC(CN[C@@H]5C)=C5C=C4)=CC=C3C1=O)=O.CS(=O)(O)=O.[H]O[H]
solubility H2O: 10 mg/mL, clear (warmed)
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: Broad spectrum fluoroquinolone antibiotic suitable for treatment of gram-positive and gram-negative bacterial infections
Biochem/physiol Actions: Garenoxacin is a broad spectrum fluoroquinolone antibiotic suitable for treatment of gram-positive and gram-negative bacterial infections. Garenoxacin has a low mutant prevention concentration and a narrow mutant selection window. Data shows that garenoxacin has anti-inflammatory properties. It significantly alleviates LPS-induced IL-8 production through the negative regulation of the ERK1/2 pathway both in the human airway epithelial cell line A549 and the monocyte cell line THP-1.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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